Watch this video...
https://www.youtube.com/watch?v=6i16HtZnQvw
The BIOS tells where the Operating System (OS) should be loaded from - Hard Disk or DVD (CDRom) or on very old machines Floppy Disk.
You do not say what happens if you actually press F1 but no matter.
The BIOS will attempt to load the OS from the place you tell it and you can dictate which.
Your BIOS is trying to load the OS from a CDRom - and there is no CDRom. So you should set it up to boot from Hard Disk.
If the hard disk is bad - in any way - you will need to rebuild the OS (operating system) on a good hard disk using the OS media and a CD disk drive.
My sign-off name is Good Luck...
June is the date...
Good Luck...
June 2016