turn the boiler off & bleed some water out of the system to lower the pressure. check that the filling loop is closed (the bit you use to top up the pressure). if the pressure is only in the red when the heating is on, then you need your expansion vessel re-pressurised.
as for your radiators, ensure that the valves on both sides of the radiators upstairs are fully open, then turn off the downstairs rads. see if that starts the upstairs radiators heating. if not, i'd suspect that you have a blockage. there is a chance that your pump could be on the road out though.
Ian
January 2010