The brakes are sticking on, Steve either due to the caliper pistons sticking, or the caliper sliding pins likewise - however you say that you have replaced the caliper.  Was it a new one?  If it was, after driving the van, jack it up on that side and see if the wheel spins freely.  If not, undo the bleed nipple a fraction, let a bit of fluid out and see if that works.  If it does, then either you have a swollen and blocked flexible pipe or a master cylinder fault.
                 John
                
 July 2009