My fridge has a fan to circulate the air - I can switch it to work or not work - it helps to even out the temperature in the cabinet.
When I open the door the fan is automatically switched off to stop the cool air being exchanged with the room air.
My fan does not make a noise - your fan is defective in some way - either a blade is touching the fan enclosure or the bearings are not as they should be.
I do not know what you mean by E1 ?
You do not mention the make or model of the fridge - not that it matters.
Consider switching the fan off if you can.
Good Luck...
December 2015