sharp xe-a301 no button will work?

Turn the key to REG mode. Press clear (CL). Type some numbers on the numeric pad. can you see the numbers on the display. If not, it probably has a faulty keyboard. Otherwise, make sure you have logged on to the machine.
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If anyone needs a Sharp XE-A301 manual, c-tech collective has them here:

User and programming manual:

http://the-checkout-tech.com/manuals/cashregisters/Sharp_XE-A301_operating_programming_manual.html

Service (repair) manual:

http://the-checkout-tech.com/manuals/cashregisters/Sharp_XE-A301_service_manual.html

Registerman
January 2011