Try a new keyboard. You should be able to go to BIOS settings (esc/del) or select boot device (F12)
Reset the motherboard to default - check your manual for this. That will put the machine in factory default, negating any changes since made. Usually a last resort when tweaking (read: overclocking) machines.
The F12 leads me to believe your HD has gone bad; try booting from the original OS (windows?) CD and do a chkdsk and attempt repair.
good luck,
Bob Smith
January 2009