Central locking unlocking car but not locking it?

Hi Paul, I have a 2005 ford focus tdci lx 5door. Problem is the key fob central locking will unlock all doors but not the boot (boot will however unlock using the separate button) but I cannot get the remote to lock the doors, neither will the key in the drivers side lock all doors (just the drivers door locks - the rest have to be locked from inside). At the same time this fault occurred - the indicators (which both work externally) show no inside signs of working either audibly or flashing light on the dashboard. Would this be fuse related?